Atletico Madrid - Sevilla - Sunday 15.00 GMT
Atletico face a Sevilla team who have yet to pick up an away win all season. Only they and Las Palmas remain winless away after half a season. Sevilla's saving grace has been nine straight home wins which leaves them still in contention for a top four finish, but obviously their away form has to improve massively to see them catch Villarreal who are currently eight points ahead.
Can they gain a first away win of the season at the Vicente Calderon? There are easier places that's for sure but Unai Emery's team do have the capability of giving Aleti a tough game. Sevilla can pick a team to match Atleti physically with the likes of Carrico, Rami, Kryckowiak, Iborra and Llorente if that's the way Emery wants to go. They also have more than their fair share of talent too with players such as Konoplyanka, Banega, Gameiro, Reyes and Vitolo. Emery has to get the balance right.
We know about Atleti's strengths, with only eight goals conceded so far in 20 games a ridiculously good record. Antoine Griezmann has been outstanding and is in great form up front, they are patient and wear teams down with their insatiable work ethic and are supremely organised with their team shape and pattern of play. In short they grind teams down.
It is going to be one of those games this weekend, I'm expecting a real genuine physical encounter with Sevilla sitting back and hoping to catch Atletico on the break, I won't be surprised to see a red card or two!
However I'm going to back Atletico with another clean sheet and a slim 1-0 win, sticking with Griezmann as the goalscorer as he hasn't let me down recently.
Atletico to win 1-0 and Griezmann to score – 17.00
Deportivo La Coruńa - Valencia - Sunday 17.15 GMT
Four without a win for Deportivo suggests that maybe their lofty hopes of a top four finish were unrealistic a month ago.
They are a team who are too reliant on one player to score a goal, that player being Lucas Perez who has 12 of the 27 they have scored so far this season. In fairness to Depor three of those four games without a win have been away from home and the lone home fixture was against high flying Villarreal so perhaps it's the week for Depor to get back on track as they face a team who haven't won a league game in nine.
Gary Neville somehow has to get his team to play a consistent 90 minutes for the first time under his leadership. If he can do that I have no doubt his team should be good enough to win this game. It is bewildering as to how Valencia can raise their game to high standards against Real Madrid and Barcelona and likewise to drag themselves back into a game when they are behind.
They have yet to be in a lead since Neville took over six La Liga games ago. These are the two defeats in which they never scored in v Real Sociedad and Villarreal, and comeback draws against Eibar, Getafe, twice behind, Real Madrid, twice behind and exactly the same last week against Rayo, trailing twice before claiming yet another draw.
This shows good spirit but why should they wait until the situation is drastic before pulling their finger out and showing signs of their true potential?
Depor will, despite being at home, look to play on the counter attack and I'm pretty sure it will be Valencia who take the game to Depor in an attempt to arrest the slide down the table. The first goal in this game is crucial.
I hate sitting on the fence but I can see another draw for Valencia, which if it wasn't for their current predicament wouldn't be a bad result.
A 1-1 draw – 7.00
Real Betis - Real Madrid - Sunday 19.30 GMT
Real Madrid ran out easy 5-0 winners in the corresponding fixture early this season at home against Pepe Mel's Real Betis. Cristiano Ronaldo wasn't among the scorers, it was one of THOSE days for him!
Since then of course Mel has lost his job and Betis are in a run of 8 La Liga games without a win and no goals in the last six. I am struggling to make a case for them to get something in this game as on top of these stats they have only managed one home win so far this season from nine games played.
I have a gut feeling though that Betis are improving under temporary coach Juan Merino. They managed a formidable result last week away from home against in form Villarreal and in doing so denied Villarreal their seventh consecutive La Liga win with a hard earned 0-0.
It was expected that Betis would appoint a new coach after that game but due to the good signs in that performance Merino is still the coach again this week. The good signs were a clean sheet, more defensive organisation and a high in terms of work rate covering a combined team total season high distance of 118km. This compares to 104 and 105 km against Barca and Real Madrid earlier in the season under Mel when they lost 4-0 and 5-0.
So harder working, more organised and backed by one of the most passionate set of supporters in Spain, I'm going to go for Betis to give Zinedine Zidane the toughest test of his fledgling career as head coach of Real Madrid. That is not much of a statement though is it, with a 5-0 and a 5-1 under his belt so far!
If Betis can deny Real early on and perhaps get to half-time without conceding, then it is not beyond the realms of possibility that they can get something from this game. Confidence and belief will build in this atmospheric stadium and it could be tough for Zidane and co, who will be missing the injured Gareth Bale.
It is tough one to call, but I'll go for Betis to get a draw.
Draw – 5.75